GJA1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human GJA1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — GJA1
Entrez GeneID
2697GeneBank Accession#
DQ893649.2Protein Accession#
ABM84575.1Gene Name
GJA1
Gene Alias
CX43, DFNB38, GJAL, ODDD
Gene Description
gap junction protein, alpha 1, 43kDa
Gene Ontology
HyperlinkGene Summary
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia and heart malformations. [provided by RefSeq
Other Designations
OTTHUMP00000017111|connexin 43|gap junction 43 kDa heart protein|gap junction protein, alpha-like
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Interactome
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Pathway
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Disease
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