GAMT purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
GAMT MaxPab polyclonal antibody. Western Blot analysis of GAMT expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of GAMT expression in transfected 293T cell line (H00002593-T01) by GAMT MaxPab polyclonal antibody.
Lane 1: GAMT transfected lysate(25.96 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GAMT protein.
Immunogen
GAMT (NP_000147.1, 1 a.a. ~ 236 a.a) full-length human protein.
Sequence
MSAPSATPIFAPGENCSPAWGAAPAAYDAADTHLRILGKPVMERWETPYMHALAAAASSKGGRVLEVGFGMAIAASKVQEAPIDEHWIIECNDGVFQRLRDWAPRQTHKVIPLKGLWEDVAPTLPDGHFDGILYDTYPLSEETWHTHQFNFIKNHAFRLLKPGGVLTYCNLTSWGELMKSKYSDITIMFEETQVPALLEAGFRRENIRTEVMALVPPADCRYYAFPQMITPLVTKG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (87)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GAMT MaxPab polyclonal antibody. Western Blot analysis of GAMT expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of GAMT expression in transfected 293T cell line (H00002593-T01) by GAMT MaxPab polyclonal antibody.
Lane 1: GAMT transfected lysate(25.96 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GAMT
Entrez GeneID
2593GeneBank Accession#
NM_000156.4Protein Accession#
NP_000147.1Gene Name
GAMT
Gene Alias
PIG2, TP53I2
Gene Description
guanidinoacetate N-methyltransferase
Omim ID
601240Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
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