FOLR2 monoclonal antibody (M04), clone 4B12
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FOLR2 is approximately 1ng/ml as a capture antibody.
Western Blot detection against Immunogen (35.97 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant FOLR2.
Immunogen
FOLR2 (NP_000794.1, 36 a.a. ~ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
HHKTKPGPEDKLHDQCSPWKKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIQQVNQTWRKERFLDVPL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (88)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.97 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FOLR2 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — FOLR2
Entrez GeneID
2350GeneBank Accession#
NM_000803Protein Accession#
NP_000794.1Gene Name
FOLR2
Gene Alias
BETA-HFR, FBP/PL-1, FR-BETA, FR-P3
Gene Description
folate receptor 2 (fetal)
Omim ID
136425Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq
Other Designations
folate receptor 2|folate receptor, beta|folate-binding protein, fetal/placental
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Interactome
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Disease
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