FKBP1B DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human FKBP1B DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQLGPLSPLPICPHPC
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — FKBP1B
Entrez GeneID
2281GeneBank Accession#
BC002614Protein Accession#
AAH02614Gene Name
FKBP1B
Gene Alias
FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase
Gene Description
FK506 binding protein 1B, 12.6 kDa
Omim ID
600620Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq
Other Designations
FK506-binding protein 1-like|FK506-binding protein 12.6|OTTHUMP00000116040|OTTHUMP00000116041|calstabin 2|immunophilin FKBP12.6|peptidyl-prolyl cis-trans isomerase|rotamase
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Interactome
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Disease
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