ECT2 monoclonal antibody (M01), clone 5D4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ECT2.
Immunogen
ECT2 (AAH06838.1, 46 a.a. ~ 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LPKENWLKMLCRHVANTICKADAENLIYTADPESFEVNTKDMDSTLSRASRAIKKTSKKVTRAFSFSKTPKRALRRALMTSHGSVEGRSPSSNDKHVMSR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86); Rat (85)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ECT2 is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — ECT2
Entrez GeneID
1894GeneBank Accession#
BC006838.1Protein Accession#
AAH06838.1Gene Name
ECT2
Gene Alias
FLJ10461, MGC138291
Gene Description
epithelial cell transforming sequence 2 oncogene
Omim ID
600586Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. [provided by RefSeq
Other Designations
epithelial cell transforming sequence 2 oncogene protein
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Interactome
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Disease
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