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DPH2 rabbit monoclonal antibody

  • Catalog # : H00001802-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human DPH2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human DPH2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human DPH2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 1802
  • GeneBank Accession#:
  • DPH2
  • Gene Name:
  • DPH2
  • Gene Alias:
  • DPH2L2
  • Gene Description:
  • DPH2 homolog (S. cerevisiae)
  • Gene Summary:
  • This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • DPH2-like 2,OTTHUMP00000010007,diphthamide biosynthesis protein 2,diphthamide biosynthesis-like protein 2,diptheria toxin resistance protein required for diphthamide biosynthesis-like 2
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