DMRT1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human DMRT1 protein.
Immunogen
DMRT1 (NP_068770.2, 1 a.a. ~ 373 a.a) full-length human protein.
Sequence
MPNDEAFSKPSTPSEAPHAPGVPPQGRAGGFGKASGALVGAASGSSAGGSSRGGGSGSGASDLGAGSKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENNGSNPCLMTECSGTSQPPPASVPTTAASEGRMVIQDIPAVTSRGHVENTPDLVSDSTYYSSFYQPSLFPYYNNLYNCPQYSMALAADSASGEVGNPLGGSPVKNSLRGLPGPYVPGQTGNQWQMKNMENRHAMSSQYRMHSYYPPPSYLGQSVPQFFTFEDAPSYPEARASVFSPPSSQDSGLVSLSSSSPISNKSTKAVLECEPASEPSSFTVTPVIEEDE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (80)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of DMRT1 expression in transfected 293T cell line (H00001761-T01) by DMRT1 MaxPab polyclonal antibody.
Lane 1: DMRT1 transfected lysate(41.03 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — DMRT1
Entrez GeneID
1761GeneBank Accession#
NM_021951.2Protein Accession#
NP_068770.2Gene Name
DMRT1
Gene Alias
DMT1
Gene Description
doublesex and mab-3 related transcription factor 1
Omim ID
602424Gene Ontology
HyperlinkGene Summary
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq
Other Designations
DM domain expressed in testis 1|OTTHUMP00000020961
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Interactomes
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Diseases
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