DMRT1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
DMRT1 transfected lysate.
Western Blot
Lane 1: DMRT1 transfected lysate ( 39.5 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-DMRT1 full-length
Host
Human
Theoretical MW (kDa)
39.5
Interspecies Antigen Sequence
Mouse (81); Rat (80)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-DMRT1 antibody (H00001761-B01) by Western Blots.
SDS-PAGE Gel
DMRT1 transfected lysate.
Western Blot
Lane 1: DMRT1 transfected lysate ( 39.5 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — DMRT1
Entrez GeneID
1761GeneBank Accession#
NM_021951.2Protein Accession#
-Gene Name
DMRT1
Gene Alias
DMT1
Gene Description
doublesex and mab-3 related transcription factor 1
Omim ID
602424Gene Ontology
HyperlinkGene Summary
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq
Other Designations
DM domain expressed in testis 1|OTTHUMP00000020961
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Interactome
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Disease
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