Rabbit monoclonal antibody raised against a human DLAT peptide using ARM Technology.
A synthetic peptide of human DLAT is used for rabbit immunization. Customer or Abnova will decide on the preferred peptide sequence.
Quality Control Testing:
Antibody reactive against human DLAT peptide by ELISA and mammalian transfected lysate by Western Blot.
In 1x PBS, pH 7.4
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
1. Customer may provide cell or tissue lysate for antibody screening. 2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
The DLAT gene encodes dihydrolipoamide acetyltransferase (EC 188.8.131.52), the E2 subunit of the mammalian pyruvate dehydrogenase complex (PDC; EC 184.108.40.206) of the inner mitochondrial membrane. Patients with primary biliary cirrhosis (PBC; MIM 109720) show autoantibodies to DLAT.[supplied by OMIM
70 kDa mitochondrial autoantigen of primary biliary cirrhosis,E2 component of pyruvate dehydrogenase complex,M2 antigen complex 70 kDa subunit