DEFA3 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human DEFA3 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSRKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — DEFA3
Entrez GeneID
1668GeneBank Accession#
NM_005217.2Protein Accession#
NP_005208.1Gene Name
DEFA3
Gene Alias
DEF3, HNP-3, HNP3, HP-3
Gene Description
defensin, alpha 3, neutrophil-specific
Omim ID
604522Gene Ontology
HyperlinkGene Summary
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. It differs from defensin, alpha 1 by only one amino acid. [provided by RefSeq
Other Designations
defensin 3, neutrophil-specific|defensin, alpha 3|neutrophil peptide 3
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