Products

Western Blot (Transfected lysate)

Immunofluorescence (Transfected cell)

Flow Cytometry (Transfected cell)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

CYP26A1

Gene Alias

CP26, CYP26, P450RAI, P450RAI1

Gene Description

cytochrome P450, family 26, subfamily A, polypeptide 1

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq

Other Designations

OTTHUMP00000020102|OTTHUMP00000020103|P450, retinoic acid-inactivating, 1|cytochrome P450, subfamily XXVIA, polypeptide 1|retinoic acid 4-hydroxylase|retinoic acid-metabolizing cytochrome