CYP26A1 recombinant monoclonal antibody, clone R02-5U3
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human Cytochrome P450 26A1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human Cytochrome P450 26A1
Theoretical MW (kDa)
Calculated MW: 56 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(1/50-1/100)
Western Blot (1/500-1/1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol and 0.02% Sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — CYP26A1
Entrez GeneID
1592Gene Name
CYP26A1
Gene Alias
CP26, CYP26, P450RAI, P450RAI1
Gene Description
cytochrome P450, family 26, subfamily A, polypeptide 1
Omim ID
602239Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000020102|OTTHUMP00000020103|P450, retinoic acid-inactivating, 1|cytochrome P450, subfamily XXVIA, polypeptide 1|retinoic acid 4-hydroxylase|retinoic acid-metabolizing cytochrome
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Interactome
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