CST6 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CST6 full-length
Host
Human
Theoretical MW (kDa)
16.5
Interspecies Antigen Sequence
Mouse (69); Rat (70)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CST6 antibody (H00001474-B01) by Western Blots.
SDS-PAGE Gel
CST6 transfected lysate.
Western Blot
Lane 1: CST6 transfected lysate ( 16.5 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CST6
Entrez GeneID
1474GeneBank Accession#
NM_001323.2Protein Accession#
NP_001314.1Gene Name
CST6
Gene Alias
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Gene Description
cystatin E/M
Omim ID
601891Gene Ontology
HyperlinkGene Summary
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype. [provided by RefSeq
Other Designations
cystatin 6|cystatin M|cystatin M/E|cysteine proteinase inhibitor
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