VCAN rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human VCAN peptide using ARM Technology.
Immunogen
A synthetic peptide of human VCAN is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human VCAN peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — VCAN
Entrez GeneID
1462GeneBank Accession#
VCANGene Name
VCAN
Gene Alias
CSPG2, DKFZp686K06110, ERVR, PG-M, WGN, WGN1
Gene Description
versican
Gene Ontology
HyperlinkGene Summary
This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Wagner syndrome (erosive vitreoretinopathy)|chondroitin sulfate proteoglycan 2 (versican)|versican proteoglycan
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