VCAN polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human VCAN.
Immunogen
Recombinant protein corresponding to human VCAN.
Sequence
SLSGKVSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebral cortex with VCAN polyclonal antibody (Cat # PAB30700) shows distinct positivity in neuropil.Immunofluorescence
Immunofluorescent staining of U-251 MG with VCAN polyclonal antibody (Cat # PAB30700) (Green) shows positivity in vesicles. -
Gene Info — VCAN
Entrez GeneID
1462Protein Accession#
P13611Gene Name
VCAN
Gene Alias
CSPG2, DKFZp686K06110, ERVR, PG-M, WGN, WGN1
Gene Description
versican
Gene Ontology
HyperlinkGene Summary
This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Wagner syndrome (erosive vitreoretinopathy)|chondroitin sulfate proteoglycan 2 (versican)|versican proteoglycan
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Interactome
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Pathway
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Disease
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