CRHR1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CRHR1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CRHR1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CRHR1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CRHR1
Entrez GeneID
1394GeneBank Accession#
CRHR1Gene Name
CRHR1
Gene Alias
CRF-R, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f
Gene Description
corticotropin releasing hormone receptor 1
Omim ID
122561Gene Ontology
HyperlinkGene Summary
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants
Other Designations
CRF1 receptor isoform I variant B|corticotropin releasing hormone receptor variant 1h|corticotropin-releasing factor receptor|seven transmembrane helix receptor
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