CREBL1 monoclonal antibody (M02), clone 4D10
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CREBL1 is approximately 1ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to ATF6B on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (35.31 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CREBL1.
Immunogen
CREBL1 (NP_004372.3, 2 a.a. ~ 88 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
AELMLLSEIADPTRFFTDNLLSPEDWGLQNSTLYSGLDEVAEEQTQLFRCPEQDVPFDGSSLDVGMDVSPSEPPWELLPIFPDLQVK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (89)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.31 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CREBL1 is approximately 1ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to ATF6B on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — ATF6B
Entrez GeneID
1388GeneBank Accession#
NM_004381Protein Accession#
NP_004372.3Gene Name
ATF6B
Gene Alias
CREB-RP, CREBL1, FLJ10066, G13
Gene Description
activating transcription factor 6 beta
Omim ID
600984Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Creb-related protein|OTTHUMP00000029433|cAMP responsive element binding protein-like 1|cyclic AMP-dependent transcription factor ATF-6 beta|protein G13
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Interactome
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Disease
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