CLDN3 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human CLDN3 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — CLDN3
Entrez GeneID
1365GeneBank Accession#
NM_001306.2Protein Accession#
NP_001297.1Gene Name
CLDN3
Gene Alias
C7orf1, CPE-R2, CPETR2, HRVP1, RVP1
Gene Description
claudin 3
Omim ID
602910Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq
Other Designations
CPE-receptor 2|Clostridium perfringens enterotoxin receptor 2|OTTHUMP00000025042|OTTHUMP00000160506|claudin-3|ventral prostate.1-like protein
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Interactome
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Pathway
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