CIDEA MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human CIDEA protein.
Immunogen
CIDEA (NP_938031.1, 1 a.a. ~ 253 a.a) full-length human protein.
Sequence
MRGDRASGGPGNHNGSWAREGPRLGPSWKRGLWSPRGGPNRPAEPSRPLTFMGSQTKRVLFTPLMHPARPFRVSNHDRSSRRGVMASSLQELISKTLDALVIATGLVTLVLEEDGTVVDTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCSPPKRSGIARVTFDLYRLNPKDFIGCLNVKATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYSAQVTGQFLIYLGTYMLRVLDDKEERPSLRSQAKGRFTCG
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CIDEA expression in transfected 293T cell line (H00001149-T01) by CIDEA MaxPab polyclonal antibody.
Lane 1: CIDEA transfected lysate(28.30 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of CIDEA transfected lysate using anti-CIDEA MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with CIDEA purified MaxPab mouse polyclonal antibody (B01P) (H00001149-B01P). -
Gene Info — CIDEA
Entrez GeneID
1149GeneBank Accession#
NM_198289Protein Accession#
NP_938031.1Gene Name
CIDEA
Gene Alias
CIDE-A
Gene Description
cell death-inducing DFFA-like effector a
Omim ID
604440Gene Ontology
HyperlinkGene Summary
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq
Other Designations
cell death activator
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Interactomes
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Diseases
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