CIDEA 293T Cell Transient Overexpression Lysate(Denatured)

Catalog # H00001149-T01

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Size:100 uL
Price: USD $ 247.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot
QC Test

Western Blot

Lane 1: CIDEA transfected lysate ( 28.3 KDa)
Lane 2: Non-transfected lysate.

SDS-PAGE Gel
QC Test

SDS-PAGE Gel

CIDEA transfected lysate.

  • Specification

    Transfected Cell Line

    293T

    Plasmid

    pCMV-CIDEA full-length

    Host

    Human

    Theoretical MW (kDa)

    27.94

    Quality Control Testing

    Transient overexpression cell lysate was tested with Anti-CIDEA antibody (H00001149-B01) by Western Blots.

    Western Blot

    Lane 1: CIDEA transfected lysate ( 28.3 KDa)
    Lane 2: Non-transfected lysate.

    SDS-PAGE Gel

    CIDEA transfected lysate.

    Storage Buffer

    1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot

  • Gene Info — CIDEA

    Entrez GeneID

    1149

    GeneBank Accession#

    NM_198289

    Protein Accession#

    NP_938031

    Gene Name

    CIDEA

    Gene Alias

    CIDE-A

    Gene Description

    cell death-inducing DFFA-like effector a

    Omim ID

    604440

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq

    Other Designations

    cell death activator

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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