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Last updated: 2017/10/22

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CES1 rabbit monoclonal antibody

  • Catalog # : H00001066-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CES1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CES1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CES1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1066
  • GeneBank Accession#:
  • CES1
  • Gene Name:
  • CES1
  • Gene Alias:
  • ACAT,CEH,CES2,HMSE,HMSE1,MGC117365,PCE-1,SES1,TGH
  • Gene Description:
  • carboxylesterase 1 (monocyte/macrophage serine esterase 1)
  • Gene Summary:
  • Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • acyl coenzyme A:cholesterol acyltransferase,carboxylesterase 1,carboxylesterase 2 (liver),cholesteryl ester hydrolase,egasyn,liver carboxylesterase,triacylglycerol hydrolase
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