CES1 monoclonal antibody, clone AECB-3
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of U-937 cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human CES1.
Immunogen
A synthetic peptide corresponding to human CES1.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human, mouse, rat CES1, in native form and recombinant. Superfamily members of CES1 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:1000-5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of U-937 cell lysate. -
Gene Info — CES1
Entrez GeneID
1066Protein Accession#
P23141Gene Name
CES1
Gene Alias
ACAT, CEH, CES2, HMSE, HMSE1, MGC117365, PCE-1, SES1, TGH
Gene Description
carboxylesterase 1 (monocyte/macrophage serine esterase 1)
Omim ID
114835Gene Ontology
HyperlinkGene Summary
Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
acyl coenzyme A:cholesterol acyltransferase|carboxylesterase 1|carboxylesterase 2 (liver)|cholesteryl ester hydrolase|egasyn|liver carboxylesterase|triacylglycerol hydrolase
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Interactome
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Pathway
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Disease
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