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CDC25C rabbit monoclonal antibody

  • Catalog # : H00000995-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CDC25C peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CDC25C is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CDC25C peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 995
  • Gene Name:
  • CDC25C
  • Gene Alias:
  • CDC25
  • Gene Description:
  • cell division cycle 25 homolog C (S. pombe)
  • Gene Summary:
  • This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq
  • Other Designations:
  • cell division cycle 25C,cell division cycle 25C protein,dual specificity phosphatase CDC25C,m-phase inducer phosphatase 3,mitosis inducer CDC25,phosphotyrosine phosphatase
  • Gene Pathway
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