BIK monoclonal antibody (M01), clone 4G12
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant BIK.
Immunogen
BIK (AAH01599, 37 a.a. ~ 136 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EDLDPMEDFDSLECMEGSDALALRLACIGDEMDVSLRAPRLAQLSEVAMHSLGLAFIYDQTEDIRDVLRSFMDGFTTLKENIMRFWRSPNPGSWVSCEQV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (50); Rat (51)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to BIK on formalin-fixed paraffin-embedded human lung. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged BIK is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — BIK
Entrez GeneID
638GeneBank Accession#
BC001599Protein Accession#
AAH01599Gene Name
BIK
Gene Alias
BIP1, BP4, NBK
Gene Description
BCL2-interacting killer (apoptosis-inducing)
Omim ID
603392Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK. [provided by RefSeq
Other Designations
BCL2-interacting killer|OTTHUMP00000028974|apoptosis-inducing NBK
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Interactome
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Disease
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