BIK polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed, paraffin-embedded tissue section of human Non-Hodgkin's lymphoma (NHL) (A) and human kidney (B) stained for BIK expression. Using BIK polyclonal antibody (Cat # PAB0239) at 1 : 2000. A high level of BIK signal was seen in the distal collecting tubules, the glomeruli are primarily negative. Hematoxylin-eosin counterstain.
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Specification
Product Description
Rabbit polyclonal antibody raised against full length recombinant BIK.
Immunogen
Recombinant protein corresponding to full length human BIK.
Host
Rabbit
Reactivity
Gerbils, Human, Mouse, Rat
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In serum (0.05% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed, paraffin-embedded tissue section of human Non-Hodgkin's lymphoma (NHL) (A) and human kidney (B) stained for BIK expression. Using BIK polyclonal antibody (Cat # PAB0239) at 1 : 2000. A high level of BIK signal was seen in the distal collecting tubules, the glomeruli are primarily negative. Hematoxylin-eosin counterstain.Immunohistochemistry (Frozen sections)
Immunoprecipitation
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Gene Info — BIK
Entrez GeneID
638Gene Name
BIK
Gene Alias
BIP1, BP4, NBK
Gene Description
BCL2-interacting killer (apoptosis-inducing)
Omim ID
603392Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK. [provided by RefSeq
Other Designations
BCL2-interacting killer|OTTHUMP00000028974|apoptosis-inducing NBK
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Interactome
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Disease
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