CRISP1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CRISP1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MEIKHLLFLVAAACLLPMLSMKKKSARDQFNKLVTDLPNVQEEIVNIHNALRRRVVPPASNMLKMSWSEEAAQNARIFSKYCDMTESNPLERRLPNTFCGENMHMTSYPVSWSSVIGVWYSESTSFKHGEWTTTDDDITTDHYTQIVWATSYLIGCAIASCRQQGSPRYLYVCHYCHEGNDPETKNEPYKTGVPCEACPSNCEDKLCTNPCIYYDEYFDCDIQVHYLGCNHSTTILFCKATCLCDTEIK
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Rat (63)
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — CRISP1
Entrez GeneID
167GeneBank Accession#
NM_001131.2Protein Accession#
NP_001122.2Gene Name
CRISP1
Gene Alias
AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP
Gene Description
cysteine-rich secretory protein 1
Omim ID
601193Gene Ontology
HyperlinkGene Summary
Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. This protein is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface. Two isoforms are encoded by transcript variants of this gene. [provided by RefSeq
Other Designations
AEG-related protein|OTTHUMP00000016592|acidic epididymal glycoprotein-like 1|cysteine-rich secretory protein-1 delta|protein DE-like
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