CRISP1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CRISP1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CRISP1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CRISP1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CRISP1
Entrez GeneID
167GeneBank Accession#
CRISP1Gene Name
CRISP1
Gene Alias
AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP
Gene Description
cysteine-rich secretory protein 1
Omim ID
601193Gene Ontology
HyperlinkGene Summary
Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. This protein is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface. Two isoforms are encoded by transcript variants of this gene. [provided by RefSeq
Other Designations
AEG-related protein|OTTHUMP00000016592|acidic epididymal glycoprotein-like 1|cysteine-rich secretory protein-1 delta|protein DE-like
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