NUT/BRD4 SY Translocation FISH Probe
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More Files
- More Functions
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
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Specification
Product Description
Labeled FISH probes for identification of gene translocation using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: NUT
Size: Approximately 530kb
Fluorophore: Texas Red
Location: 15q14Probe 2
Name: BRD4
Size: Approximately 730kb
Fluorophore: FITC
Location: 19p13.1Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulatory Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome.
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — BRD4
Entrez GeneID
23476Gene Name
BRD4
Gene Alias
CAP, HUNK1, HUNKI, MCAP
Gene Description
bromodomain containing 4
Omim ID
608749Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
bromodomain-containing 4|bromodomain-containing protein 4|chromosome-associated protein
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Gene Info — C15orf55
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Interactome
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