RREB1/MAP3K10 Translocation FISH Probe
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More Files
- More Functions
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
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Specification
Product Description
Labeled FISH probes for identification of gene translocation using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: RREB1
Size: Approximately 610kb
Fluorophore: FITC
Location: 6p24.3Probe 2
Name: MAP3K10
Size: Approximately 560kb
Fluorophore: Texas Red
Location: 16p13.12Origin
Human
Source
Genomic DNA
Reactivity
Human
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulatory Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome.
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — MAP3K10
Entrez GeneID
4294Gene Name
MAP3K10
Gene Alias
MLK2, MST
Gene Description
mitogen-activated protein kinase kinase kinase 10
Omim ID
600137Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq
Other Designations
MKN28 derived nonreceptor_type serine/threonine kinase|MKN28 kinase|mixed lineage kinase 2
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Gene Info — RREB1
Entrez GeneID
6239Gene Name
RREB1
Gene Alias
FINB, HNT, LZ321, RREB-1, Zep-1
Gene Description
ras responsive element binding protein 1
Omim ID
602209Gene Ontology
HyperlinkOther Designations
DNA-binding protein|finger protein in nuclear bodies|hindsight homolog|zinc finger motif enhancer binding protein 1
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Interactome
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Pathway
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Disease
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