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Last updated: 2020/7/12

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MYB/NFIB Translocation FISH Probe 

  • Catalog # : FT0037
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene translocation using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FT0037
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome.

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • MYB
    Approximately 1010kb
    FITC
    6q22-23
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • NFIB
    Approximately 1090kb
    Texas Red
    9p24.1
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulatory Status:
  • For research use only (RUO)
  • Applications
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Gene Information
  • Entrez GeneID:
  • 4602
  • Gene Name:
  • MYB
  • Gene Alias:
  • Cmyb,c-myb,c-myb_CDS,efg
  • Gene Description:
  • v-myb myeloblastosis viral oncogene homolog (avian)
  • Gene Summary:
  • This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • Avian myeloblastosis viral (v-myb) oncogene homolog,OTTHUMP00000017258,c-myb protein (140 AA),c-myb10A_CDS,c-myb13A_CDS,c-myb14A_CDS,c-myb8B_CDS,v-myb avian myeloblastosis viral oncogene homolog,v-myb myeloblastosis viral oncogene homolog
  • Gene Information
  • Entrez GeneID:
  • 4781
  • Gene Name:
  • NFIB
  • Gene Alias:
  • HMGIC/NFIB,NFI-RED,NFIB2,NFIB3
  • Gene Description:
  • nuclear factor I/B
  • Other Designations:
  • OTTHUMP00000022765,OTTHUMP00000044928
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