MEF2D/BCL9 Translocation FISH Probe
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More Files
- More Functions
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
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Specification
Product Description
Labeled FISH probes for identification of gene translocation using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: MEF2D
Size: Approximately 1610kb
Fluorophore: FITC
Location: 1q12-23Probe 2
Name: BCL9
Size: Approximately 710kb
Fluorophore: Texas Red
Location: 1q21Origin
Human
Source
Genomic DNA
Reactivity
Human
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulatory Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome.
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — BCL9
Entrez GeneID
607Gene Name
BCL9
Gene Alias
LGS, MGC131591
Gene Description
B-cell CLL/lymphoma 9
Omim ID
602597Gene Ontology
HyperlinkGene Summary
BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies. [provided by RefSeq
Other Designations
OTTHUMP00000015909
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Gene Info — MEF2D
Entrez GeneID
4209Gene Name
MEF2D
Gene Alias
DKFZp686I1536
Gene Description
myocyte enhancer factor 2D
Omim ID
600663Gene Ontology
HyperlinkGene Summary
polypeptide D (myocyte enhancer factor 2D)|MEF2D/DAZAP1 fusion|OTTHUMP00000031810|myocyte enhancer factor 2D/deleted in azoospermia associated protein 1 fusion protein
Other Designations
MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D)|MEF2D/DAZAP1 fusion|OTTHUMP00000031810|myocyte enhancer factor 2D/deleted in azoospermia associated protein 1 fusion protein
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Interactome
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Disease
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