NFIB/TCF3 SY Translocation FISH Probe
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Hybridization position of the probes on the chromosome:
Hybridization position of the probes on the chromosome:
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Specification
Product Description
Labeled FISH probes for identification of gene transloaction using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: NFIB
Size: Approximately 500kb
Fluorophore: Texas Red
Location: 9p24.1Probe 2
Name: TCF3
Size: Approximately 720kb
Fluorophore: FITC
Location: 19p13.3Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome:
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — NFIB
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Gene Info — TCF3
Entrez GeneID
6929Gene Name
TCF3
Gene Alias
E2A, ITF1, MGC129647, MGC129648, bHLHb21
Gene Description
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
Omim ID
147141Gene Ontology
HyperlinkGene Summary
The TCF3 gene, also called E2A, encodes 2 basic helix-loop-helix (bHLH) transcription factors, E12 and E47, through alternative splicing. E12 and E47 are involved in regulation of immunoglobulin gene expression (Bain et al., 1994 [PubMed 8001125]).[supplied by OMIM
Other Designations
E2A immunoglobulin enhancer-binding factor E12/E47|immunoglobulin transcription factor 1|kappa-E2-binding factor|transcription factor 3|transcription factor E2-alpha
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Interactome
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Disease
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