Labeled FISH probes for identification of gene split using Fluoresecent In Situ Hybridization Technique. (Technology) The 50 uL format is now available until 2014/12/31, this format does not contain DAPI Counterstain. (Please contact us for more information.)
Quality Control Testing:
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
DAPI Counterstain (1500 ng/mL ) 250 uL
Store at 4°C in the dark.
Hybridization position of the probes on the chromosome.
Probe 1: Size: Fluorophore: Location:
TFE3(Texas Red) Approximately 570kb Texas Red Xp11.22
Probe 2: Size: Fluorophore: Location:
TFE3(FITC) Approximately 550kb FITC Xp11.22
The gap between two probes is approximately 90 kb.
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
TFE3, a member of the helix-loop-helix family of transcription factors, binds to the mu-E3 motif of the immunoglobulin heavy-chain enhancer and is expressed in many cell types (Henthorn et al., 1991 [PubMed 1685140]).[supplied by OMIM
OTTHUMP00000024272,Renal cell carcinoma, papillary,Transcription factor for IgH enhancer,transcription factor E family, member A,transcription factor E3