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Last updated: 2019/9/15

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mutaFISH™ IFNGwt RNA Probes 

  • Catalog # : FP0031
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  • Specification
  • Product Description:
  • mutaFISH™ IFNGwt RNA Probes is designed to detect human IFNG gene on single strand RNA in cells using padlock probe and in situ rolling-circle amplification technology.
  • Supplied Product:
  • Content:

    1. RT IFNG Primer

    2. mutaFISH™ IFNGwt RNA Probe

    3. Detection Probe-FITC
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • We recommend mutaFISH™ RNA Accessory Kit (Catalog #: KA4915) which provides necessary reagents and enzymes for in situ reverse transcription, RNA digestion, mutaFISH™ hybridization, ligation and amplication prior to mutaFISH™.
  • Fluorophore:
  • FITC (Excitation Peak (nm): 495; Emission Peak (nm): 519)
  • Probe Position:
  • Regulatory Status:
  • For research use only (RUO)
  • Video:
  • Applications
  • mutation specific, Fluorescence In Situ Hybridization (Cells)
  • mutation specific, Fluorescence <em>In Situ</em> Hybridization (Cells)
  • mutaFISH™ staining was performed in situ in IFNG transfected 293T cells. IFNG gene was detected via green signal (FITC).
  • Application Image
  • mutation specific, Fluorescence In Situ Hybridization (Cells)
  • mutation specific, Fluorescence <em>In Situ</em> Hybridization (Cells)
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  • Gene Information
  • Entrez GeneID:
  • 3458
  • Gene Name:
  • IFNG
  • Gene Alias:
  • IFG,IFI
  • Gene Description:
  • interferon, gamma
  • Gene Summary:
  • Interferon-gamma (IFNG), or type II interferon, is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFNG in the immune system stems in part from its ability to inhibit viral replication directly, but most importantly derives from its immunostimulatory and immunomodulatory effects. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 (MIM 186940) and CD8 (see MIM 186910) cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops (Schoenborn and Wilson, 2007 [PubMed 17981204]).[supplied by OMIM
  • Other Designations:
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