XIST/CENXp FISH Probe
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
-
Specification
Product Description
Labeled FISH probes for identification of gene translocation using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: XIST1
Size: Approximately 150kb
Fluorophore: Texas Red
Location: Xq13.2Probe 2
Name: CENXp
Size: Approximately 550kb
Fluorophore: FITC
Location: Xp11.22Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulatory Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome.
-
Applications
Fluorescent In Situ Hybridization (Cell)
-
Gene Info — XIST
Entrez GeneID
7503Gene Name
XIST
Gene Alias
DKFZp779P0129, DXS1089, DXS399E, NCRNA00001, SXI1, XCE, XIC, swd66
Gene Description
X (inactive)-specific transcript (non-protein coding)
Gene Ontology
HyperlinkGene Summary
X inactivation is an early developmental process in mammalian females that transcriptionally silences one of the pair of X chromosomes, thus providing dosage equivalence between males and females. The process is regulated by several factors, including a region of chromosome X called the X inactivation center (XIC). The XIST gene is expressed exclusively from the XIC of the inactive X chromosome. The transcript is spliced but apparently does not encode a protein. The transcript remains in the nucleus where it coats the inactive X chromosome. Alternatively spliced transcript variants have been identified, but their full length sequences have not been determined. Mutations in the XIST promoter cause familial skewed X inactivation. [provided by RefSeq
Other Designations
-
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com