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Last updated: 2021/6/20

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EED/CEN11p FISH Probe 

  • Catalog # : FG0251
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FG0251
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Note:
  • Hybridization position of the probes on the chromosome.

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • EED
    Approximately 260kb
    Texas Red
    11q14.2
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • CEN11p
    Approximately 630kb
    FITC
    11p11.12
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulatory Status:
  • For research use only (RUO)
  • Applications
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Gene Information
  • Entrez GeneID:
  • 8726
  • Gene Name:
  • EED
  • Gene Alias:
  • HEED,WAIT1
  • Gene Description:
  • embryonic ectoderm development
  • Gene Summary:
  • This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • WD protein associating with integrin cytoplasmic tails 1
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