LAMA3 FISH Probe
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Specification
Product Description
Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Origin
Human
Source
Genomic DNA
Reactivity
Human
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Supplied Product
DAPI Counterstain (1500 ng/mL ) 250 uL
Storage Instruction
Store at 4°C in the dark.
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — LAMA3
Entrez GeneID
3909Gene Name
LAMA3
Gene Alias
BM600, E170, LAMNA, LOCS, lama3a
Gene Description
laminin, alpha 3
Gene Ontology
HyperlinkGene Summary
Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. The protein encoded by this gene is the alpha-3 subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
BM600 150kD subunit|epiligrin 170 kda subunit|epiligrin alpha 3 subunit|kalinin 165kD subunit|laminin alpha 3 subunit|laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin)|laminin-5 alpha 3 chain|nicein 150kD subunit
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Interactome
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Disease
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