SCN1A FISH Probe
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Specification
Product Description
Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Origin
Human
Source
Genomic DNA
Reactivity
Human
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Supplied Product
DAPI Counterstain (1500 ng/mL ) 250 uL
Storage Instruction
Store at 4°C in the dark.
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — SCN1A
Entrez GeneID
6323Gene Name
SCN1A
Gene Alias
FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI
Gene Description
sodium channel, voltage-gated, type I, alpha subunit
Gene Ontology
HyperlinkGene Summary
The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders
Other Designations
febrile convulsions 3|sodium channel protein, brain I alpha subunit|sodium channel, voltage-gated, type I, alpha|sodium channel, voltage-gated, type I, alpha polypeptide
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