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Last updated: 2014/11/16
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ATF4 polyclonal antibody

  • Catalog # : PAB4874
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ATF4.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S245 of human ATF4.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of ATF4 (arrow) using rabbit ATF4 polyclonal antibody (Cat # PAB4874). 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ATF4 gene (Lane 2) (Origene Technologies).
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 468
  • Protein Accession#:
  • NP_001666;Q96AQ3
  • Gene Name:
  • ATF4
  • Gene Alias:
  • CREB-2,CREB2,TAXREB67,TXREB
  • Gene Description:
  • activating transcription factor 4 (tax-responsive enhancer element B67)
  • Gene Summary:
  • This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication. [provided by RefSeq
  • Other Designations:
  • activating transcription factor 4,cAMP response element-binding protein 2
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