USP28 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of USP28.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human USP28.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
The USP28 polyclonal antibody (Cat # PAB4217) is used in Western blot to detect USP28 in Jurkat cell lysate .Enzyme-linked Immunoabsorbent Assay
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Gene Info — USP28
Entrez GeneID
57646Protein Accession#
UB28_HUMANGene Name
USP28
Gene Alias
KIAA1515
Gene Description
ubiquitin specific peptidase 28
Omim ID
610748Gene Ontology
HyperlinkGene Summary
The ubiquitin-dependent protein degradation pathway is essential for proteolysis of intracellular proteins and peptides. Enzymes that remove ubiquitin from ubiquitin-conjugated peptides, like USP28, affect the fate and degradation of intracellular proteins and are essential for maintenance of cell-free ubiquitin pools (Valero et al., 2001).[supplied by OMIM
Other Designations
ubiquitin specific protease 28
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Interactomes
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Publication Reference
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Human and mouse proteases: a comparative genomic approach.
Puente XS, Sanchez LM, Overall CM, Lopez-Otin C.
Nature Reviews. Genetics 2003 Jul; 4(7):544.
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Characterization of alternatively spliced products and tissue-specific isoforms of USP28 and USP25.
Valero R, Bayes M, Francisca Sanchez-Font M, Gonzalez-Angulo O, Gonzalez-Duarte R, Marfany G.
Genome Biology 2001 Sep; 2(10):RESEARCH00.
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Human and mouse proteases: a comparative genomic approach.
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