SOX8/SOX9/SOX17/SOX18 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
Western blot analysis of COS-7 cell lysate with SOX8/SOX9/SOX17/SOX18 polyclonal antibody (Cat # PAB26962).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using SOX8/SOX9/SOX17/SOX18 polyclonal antibody (Cat # PAB26962).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SOX8/SOX9/SOX17/SOX18.
Immunogen
A synthetic peptide corresponding to human SOX8/SOX9/SOX17/SOX18.
Host
Rabbit
Theoretical MW (kDa)
47
Reactivity
Human, Mouse
Specificity
SOX8/SOX9/SOX17/SOX18 polyclonal antibody detects endogenous levels of SOX8/SOX9/SOX17/SOX18 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of COS-7 cell lysate with SOX8/SOX9/SOX17/SOX18 polyclonal antibody (Cat # PAB26962).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using SOX8/SOX9/SOX17/SOX18 polyclonal antibody (Cat # PAB26962). -
Gene Info — SOX9
Entrez GeneID
6662Protein Accession#
P57073(Gene ID : 30812);P48436(Gene ID : 6662);Q9H6I2(Gene ID : 64321);P35713(Gene ID : 54345)Gene Name
SOX9
Gene Alias
CMD1, CMPD1, SRA1
Gene Description
SRY (sex determining region Y)-box 9
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq
Other Designations
SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)|SRY (sex-determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)|SRY (sex-determining region Y)-box 9 protein|campomelic dysplasia, autosomal sex-revers
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Gene Info — SOX8
Entrez GeneID
30812Protein Accession#
P57073(Gene ID : 30812);P48436(Gene ID : 6662);Q9H6I2(Gene ID : 64321);P35713(Gene ID : 54345)Gene Name
SOX8
Gene Alias
MGC24837
Gene Description
SRY (sex determining region Y)-box 8
Omim ID
605923Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). [provided by RefSeq
Other Designations
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Gene Info — SOX18
Entrez GeneID
54345Protein Accession#
P57073(Gene ID : 30812);P48436(Gene ID : 6662);Q9H6I2(Gene ID : 64321);P35713(Gene ID : 54345)Gene Name
SOX18
Gene Alias
HLTS
Gene Description
SRY (sex determining region Y)-box 18
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. [provided by RefSeq
Other Designations
OTTHUMP00000031624|SRY-box 18|Transcription factor SOX-18
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Gene Info — SOX17
Entrez GeneID
64321Protein Accession#
P57073(Gene ID : 30812);P48436(Gene ID : 6662);Q9H6I2(Gene ID : 64321);P35713(Gene ID : 54345)Gene Name
SOX17
Gene Alias
FLJ22252
Gene Description
SRY (sex determining region Y)-box 17
Omim ID
610928Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq
Other Designations
SRY-box 17|SRY-related HMG-box transcription factor SOX17
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Disease
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