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MMP14 polyclonal antibody   

  • Catalog # : PAB18771
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  • 100 ug
  • USD $ 319
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  • Email : sales@abnova.com
    Phone : +1-909-992-0619 (new)
    Fax : +1-909-992-3401
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of MMP14.
  • Immunogen:
  • A synthetic peptide corresponding to 14 amino acids at internal region of human MMP14.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Recommend Usage:
  • ELISA (1:10000-1:10000)
    Western Blot (1:200-1:500)
    Immunohistochemistry (1:50-1:500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In buffer containing 0.02% sodium azide, 2% BSA
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of MCF-7 cell lysate with MMP14 polyclonal antibody (Cat # PAB18771) at 1 : 200 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of formalin-fixed paraffin-embedded human breast carcinoma tissue showing cytoplasmic staining with MMP14 polyclonal antibody (Cat # PAB18771) at 1 : 100 dilution.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4323
  • Gene Name:
  • MMP14
  • Gene Alias:
  • MMP-X1,MT1-MMP,MTMMP1
  • Gene Description:
  • matrix metallopeptidase 14 (membrane-inserted)
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq
  • Other Designations:
  • matrix metalloproteinase 14,matrix metalloproteinase 14 (membrane-inserted),membrane type 1 metalloprotease,membrane-type matrix metalloproteinase 1,membrane-type-1 matrix metalloproteinase
  • Gene Pathway
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