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BIOtech
BULK-new

BCL2L1 (phospho T115) polyclonal antibody

  • Catalog # : PAB16883
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of BCL2L1 .
  • Immunogen:
  • Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T115 of BCL2L1 .
  • Sequence:
  • TSQLHITpPGTAY
  • Host:
  • Rabbit
  • Reactivity:
  • Mouse
  • Form:
  • Lyophilized
  • Recommend Usage:
  • ELISA (1:10000-1:100000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 10 mM PBS
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 598
  • Gene Name:
  • BCL2L1
  • Gene Alias:
  • BCL-XL/S,BCL2L,BCLX,Bcl-X,DKFZp781P2092,bcl-xL,bcl-xS
  • Gene Description:
  • BCL2-like 1
  • Gene Summary:
  • The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000030550,OTTHUMP00000030551,OTTHUMP00000030553
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