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CSF2 (Human) Recombinant ProteinBioActive

  • Catalog # : P3614
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  • Specification
  • Product Description:
  • Human CSF2 (P04141, 1 a.a. - 144 a.a.) full-length recombinant protein. expressed in Escherichia coli.
  • Sequence:
  • MWLQSLLLLGTVACSISAPARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVISEMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLTMMASHYKQHCPPTPETSCATQIITFESFKENLKDFLLVIPFDCWEPVQE
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 15
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purification:
  • Ion exchange column and HPLC reverse phase column
  • Purity:
  • > 96% by SDS-PAGE and HPLC
  • Endotoxin Level:
  • < 0.1 ng/ug (1 EU/ug)
  • Activity:
  • The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤0.1 ng/mL, corresponding to a specific activity of ≥ 1 x 107 units/mg.
  • Storage Buffer:
  • Lyophilized from PBS, pH 7.0
  • Storage Instruction:
  • Store at -20°C on dry atmosphere for 2 years.
    After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 1437
  • Gene Name:
  • CSF2
  • Gene Alias:
  • GMCSF,MGC131935,MGC138897
  • Gene Description:
  • colony stimulating factor 2 (granulocyte-macrophage)
  • Gene Summary:
  • The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq
  • Other Designations:
  • colony stimulating factor 2,granulocyte-macrophage colony stimulating factor,molgramostin,sargramostim
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