AFP monoclonal antibody, clone AFP-Y1
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Specification
Product Description
Mouse monoclonal antibody raised against native AFP.
Immunogen
Native purified human amniotic fluid AFP.
Host
Mouse
Reactivity
Human
Specificity
This antibody has no detectable cross-reaction with human normal serum proteins.
Form
Lyophilized
Isotype
IgG1
Recommend Usage
Sandwich ELISA (Capture Coating Dose: 0.1 ug/well)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 10 mM PBS, pH 7.0
Storage Instruction
Store at -20°C.
Aliquot after reconstitution to avoid repeated freezing and thawing. -
Applications
Immunoprecipitation
Sandwich ELISA
Capture Antibody
Radioimmunoassay
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Gene Info — AFP
Entrez GeneID
174Gene Name
AFP
Gene Alias
FETA, HPAFP
Gene Description
alpha-fetoprotein
Omim ID
104150Gene Ontology
HyperlinkGene Summary
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq
Other Designations
OTTHUMP00000160480|alpha-1-fetoprotein|alpha-fetoglobulin
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Interactome
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Disease
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