IL16 monoclonal antibody, clone 1F12D7
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Specifications
Product Description
Mouse monoclonal antibody raised against recombinant IL16.
Immunogen
Recombinant protein corresponding to IL16.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis using IL16 monoclonal antibody, clone 1F12D7 (Cat # MAB5590) against truncated IL16 recombinant protein.Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL16
Entrez GeneID
3603Gene Name
IL16
Gene Alias
FLJ16806, FLJ42735, FLJ44234, HsT19289, IL-16, LCF, prIL-16
Gene Description
interleukin 16 (lymphocyte chemoattractant factor)
Omim ID
603035Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000190849|OTTHUMP00000190850|interleukin 16|lymphocyte chemoattractant factor
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Interactomes
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Diseases
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Publication Reference
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Molecular and functional analysis of a lymphocyte chemoattractant factor: association of biologic function with CD4 expression.
Cruikshank WW, Center DM, Nisar N, Wu M, Natke B, Theodore AC, Kornfeld H.
PNAS 1994 May; 91(11):5109.
Application:WB, Recombinant protein.
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Molecular and functional analysis of a lymphocyte chemoattractant factor: association of biologic function with CD4 expression.
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