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C-peptide monoclonal antibody, clone C-PEP-01 (Biotin)   

  • Catalog # : MAB5025
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  • 100 ug
  • USD $ 319
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against C-peptide.
  • Immunogen:
  • Human C-peptide conjugated with BSA.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts specifically with C-peptide, a part of the Proinsulin molecule. Proinsulin consists of the three parts: C-peptide and two long strands of amino acids (alpha and beta chains; later become linked together to form the Insulin molecule). No cross-reactivity with Insulin or other peptide hormones or proteins was observed.
  • Form:
  • Liquid
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunohistochemistry (25 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (15 mM sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 3630
  • Gene Name:
  • INS
  • Gene Alias:
  • ILPR,IRDN
  • Gene Description:
  • insulin
  • Gene Summary:
  • After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000011161,OTTHUMP00000011162,OTTHUMP00000196038,proinsulin
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