INS recombinant monoclonal antibody, clone 1F6
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human INS.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human INS.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemical staining of human pancreatic cancer with INS recombinant monoclonal antibody, clone 1F6 (Cat # RAB04387) (diluated at 1:100).Immunohistochemistry
Immunohistochemical staining of human pancreatic tissue with INS recombinant monoclonal antibody, clone 1F6 (Cat # RAB04387) (diluated at 1:100).Enzyme-linked Immunoabsorbent Assay
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Gene Info — INS
Entrez GeneID
3630Protein Accession#
P01308Gene Name
INS
Gene Alias
ILPR, IRDN
Gene Description
insulin
Gene Ontology
HyperlinkGene Summary
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq
Other Designations
OTTHUMP00000011161|OTTHUMP00000011162|OTTHUMP00000196038|proinsulin
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Interactome
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Disease
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