LRP1 monoclonal antibody, clone MA5A6
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Specification
Product Description
Mouse monoclonal antibody raised against LRP1.
Immunogen
Human 85 kDa low density LRP1.
Host
Mouse
Theoretical MW (kDa)
~38
Reactivity
Human, Mouse, Rabbit
Specificity
This purified mouse monoclonal antibody cross reacts with human, mouse, and rabbit and is specific to the 85 KDa light chain of LDL Receptor-Related Protein (LRP).
Form
Liquid
Isotype
IgG2b
Recommend Usage
Western Blot (1-5 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM sodium phosphate buffer, 150 mM NaCl, 1 mM EDTA, pH 6.6.
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Frozen sections)
Flow Cytometry
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Gene Info — LRP1
Entrez GeneID
4035Gene Name
LRP1
Gene Alias
A2MR, APOER, APR, CD91, FLJ16451, IGFBP3R, LRP, MGC88725, TGFBR5
Gene Description
low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
Omim ID
107770Gene Ontology
HyperlinkOther Designations
TbetaR-V/LRP-1/IGFBP-3 receptor|alpha-2-macroglobulin receptor|low density lipoprotein-related protein 1|type V tgf-beta receptor
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Interactome
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Disease
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Publication Reference
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Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the 39-kd receptor-associated protein in human trophoblasts.
Coukos G, Gåfvels ME, Wisel S, Ruelaz EA, Strickland DK, Strauss JF 3rd, Coutifaris C.
The American Journal of Pathology 1994 Feb; 144(2):383.
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Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions.
Rebeck GW, Reiter JS, Strickland DK, Hyman BT.
Neuron 1993 Oct; 11(4):575.
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Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.
Strickland DK, Ashcom JD, Williams S, Burgess WH, Migliorini M, Argraves WS.
The Journal of Biological Chemistry 1990 Oct; 265(29):17401.
Application:ELISA, IP, WB-Ce, WB-Re, Human, Human gingival fibroblasts, Purified proteins.
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Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the 39-kd receptor-associated protein in human trophoblasts.
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