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Last updated: 2014/9/29
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MYC monoclonal antibody, clone IMD-3

  • Catalog # : MAB1446
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of MYC.
  • Immunogen:
  • A synthetic peptide corresponding to human MYC.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 62
  • Reactivity:
  • Human
  • Form:
  • Lyophilized
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG2a
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (4 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (8 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 1.2% sodium acetate (2 mg BSA, 0.01 mg sodium azide)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 1 mL of 1.2% sodium acetate or neutral PBS and concentration will be 100 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunocytochemistry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunocytochemistry
  • Gene Information
  • Entrez GeneID:
  • 4609
  • Gene Name:
  • MYC
  • Gene Alias:
  • bHLHe39,c-Myc
  • Gene Description:
  • v-myc myelocytomatosis viral oncogene homolog (avian)
  • Gene Summary:
  • The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq
  • Other Designations:
  • avian myelocytomatosis viral oncogene homolog,myc proto-oncogene protein,v-myc avian myelocytomatosis viral oncogene homolog
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